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Re:Rents in Megacities Can't Go Up Forever by logfromblammo on Thursday March 23, 2017 @12:07PM (#13941036)
Chicago is the "second city" in a lot of things. These are the top public companies in the city:

  Aerospace/Defense: Boeing
  Agribusiness/Foodservice: ADM, Mondelez, McDonald's, US Foods, Ingredion
  Communications:  Anixter, Motorola, TDS
  Energy: Exelon
  Finance: Discover, JLL
  Healthcare: Walgreens, AbbVie, Abbott, Baxter, Baxalta
  Industrial/Manufacturing/B2B: ITW, CDW, Navistar, Grainger, Univar, Tenneco, LKQ, Dover, Packaging Corp., Essendant
  Insurance: State Farm, Allstate, Old Republic, AJG
  Publishing: RR Donnelley
  Retail: Sears
  Transport: United
Apparently, Chicago excels in insurance, food, and manufacturing support.

If you intend to create technology for supporting businesses in those sectors, having a Chicago office would not be a bad idea. SV unicorns tend not to even want to solve problems like how to more efficiently route a single gigantic monolithic I-beam from the foundry to a building site without destroying buildings, bridges, and roads along the way. It isn't sexy, and doesn't attract money or eager and idealistic employees.

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