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Re:Your yearly dose of is-the-universe-a-simulation by coldtea on Wednesday March 22, 2017 @08:07AM (#13930222)
Check e.g.:

https://en.wikipedia.org/wiki/The_Structure_of_Scientific_Re...

https://en.wikipedia.org/wiki/Against_Method

(And other newer sources on epistemology, but those are basic).

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