Not only is it not falsifiable it provides nothing actionable whatsoever. Accepting the statement as fact changes nothing practical unless you're the nihilistic type and look for an excuse to go on a spree killing or to off yourself -- or you're bogged down by anxiety and the revelation that nothing matters frees you to live without care, which I find unlikely.

It's basically a philosophical game of navel gazing. I get why some might find that enjoyable but to imply it has any practical application seems nonsensical. It's like debating how long God's beard is or what material a unicorn's horn is made of.