Cellulose absent water is extremely inert, so inert that we use it as long term information storage, it is also an extremely good insulator.
You'd be more likely looking at using the cellulose as a non-conducting carrier than as part of the logic itself.
Would you be able to sacrifice some of the raw "speed" you gain from using electrical current to carry the signals in a traditional PCB if it meant you could work with significantly reduced heat? Or is my rudimentary understanding of the physics here betraying me? Friction is going to exist, so it's quite possible that these types of organic fluid logic gates would be useful for other reasons, but not in the ways I've imagined.
Without some(all?) of the electromagnetic changes associated with the continued reduction of die size for traditional electrical circuits, can you build significantly denser (and eventually more powerful) mechanical circuits with fluid-filled cellulose nanotubes?
Any kind of acidity would also be taboo. It would be very hard I think to make something like this but I'm more than willing to admit that none of these are 'dealbreakers'. That's why I asked about the application, after all, if that's the only way to do it and the application is valuable enough then maybe there is a reason to invest a large amount of $ for R&D.