I've been prescribed opioids twice in my life, once for wisdom teeth extraction and again for a broken ankle. In the first case I filled the prescription but ended up flushing the pills down the toilet without taking a single one, as the pain did not override my fear of developing dependency. I never even filled the prescription for the broken ankle, and also didn't need it.

These should be treated as treatments of last, not first resort. In both cases, marijuana would have been a more appropriate for pain relief anyway (though I did not use any).