I think this expectation has mostly dropped away in the last couple years. A lot of apps now have interfaces inspired by apps (e.g. Airmail on Mac OS X acts like an iPad app) or web apps (all the Electron apps). Obviously this isn't saying that a personal dislike for it is wrong, I just think that it's becoming less important in the market.

This might be true for standard consumer applications that can fit within the web paradigm. However, you then fail to be able to leverage vendor specific interaction paradigms, which is something I want to be able to do, such as the Mac touch strip, the Windows Surface Dial and Pen, or the Gnome title bar/notifications/messaging interface. I like to interact with voice services, so you need something for this as well, or handling the various HiDPI features of each system.

RIDE is already quite good. It is simple and effective and in a sense better than jupyter. Throw in some D3 they would get the graphical capabilities, just like how jhs does it.

A comercial example? Mathematica.

Imagine a Mathematica clone with APL...

I'm actually designing one better. :-) Probably a few years out from true production ready (maybe more, who am I kidding, probably more), but definition something cool.