I don't want them on a 'per-application' basis.

The older macs, you could have f-key 'default' with the other options activated by holding the FN key, or reverse it, so that the brightness/etc were default, and f-keys activated by holding down the FN key.

There is no option to just have f-keys defaulted, with other touchbar stuff activated by FN key. For people who simply want standard f-keys as default all the time (like you could have in the previous macs), there is no option right now.

You can't, actually. This only works for some applications. None of my WINE apps, for example, can have this enabled. Apple failed.