I've found Twitter feeds more timely than status-light dashboards for various online services. Partly because the users start to scream before the SREs update their blinken lights.

I was vaguely interested in it (Twitter) when the Iranian purple revolution was going on, but that passed, and after that version of tweetdeck did as well, I've never been able to track topics well enough to make it more worth-while (to me) than a meme-tracker.

Other than that, I haven't found much use of it. I'm guessing that puts me in the dissenting position, but this isn't the first time that's happened.