So, even before iTunes existed, you'd probably have difficulty starting a startup which was supposed to do what iTunes does now, since without the iPod and Apple's negotiating power, you're left with a file downloading utility with DRM and no songs from major records, and nobody wants that. So iTunes not only isn't a tool, it isn't a startup-applicable idea; nobody would shy away from doing iTunes because it's a non-social-network application, because they wouldn't try to do iTunes to begin with.
Edit: Anyway, I think it's reasonable to think that a lot of the obvious straight-web-tools genres are well-done enough already that you'd have difficulty starting a startup in one. There might be whole new markets for straight tools out there for the taking, but they're at the very least harder to think of than they were in 1995. A lot of the equivalently easy-to-think-of social applications are just now getting off the ground, so the whole essay kind of makes sense.
The most interesting thing about the article to me is that it seems to imply a theory of waves of market gaps closing, and that maybe each market gap gets created by the closing of the one before it. There was a market gap for PCs, then that got (more or less) filled, which created a market gap for connectivity, the filling of which created a market gap for web tools, and now that closing has created a market gap for social tools. It could be totally bunk, but it's fun to think about anyway.
So now for a while everything "social" will survive for a while, untill the big players have manifested themselves.
Anyway, I didn't want to make a point for iTunes, just "prove" that social networks are not the only kind of applications successful today.