I don't use an ad-blocker (yet). But when the day comes that I do install one, it will be exactly this that drives me over the edge. As far as I'm concerned, the author(s) of any website who auto-play any audio content need to be shot, hung, drawn, quartered, tarred, feathered, and then burn in the lowest level of hell for all eternity.

I don't care about banner ads, re-targeting, etc., etc. But if you fucking hijack my speakers/headphones to play some random shit I don't want to hear, I hope you die a painful, slow, lingering death.