Keyboard mostly a non-issue, as I use a mech, but it's not bad, just different. My Logitech BT mouse disconnects, but that's a Sierra issue, as it happened on my previous machine (and is a documented issue with Logitech apparently). Monitor support is wonky, but not too bad if you stick with only DisplayPort with a DP->USBC cable or use the official Apple dongle with HDMI. Apple's TB display works great with the TB2->TB3 adapter. (Eagerly anticipating the TB3 docks coming out later in the year)

On TouchBar: Yes, it definitely has its advantages and disadvantages. I dig the touch ID login. Escape key issue only annoyed me a time or two, but I'm not a heavy VIM user, and the ESC key is actually wider than most people realize (space to left of it is actually additional touch target for the key, so you actually have an easier to type ESC key in actuality)