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Re:Researchers use music and LSD to understand how we attrib... by shaki-dora on Tuesday January 31, 2017 @01:20AM (#13528210)
It should be "the [..] receptor-antagonist ketanserin" (can't take a dose of a receptor). And the effect isn't complete if I understand it correctly. But higher doses or a more potent antagonist could block the psychedelic effects completely, yes.

I'm not quite sure if LSD has non-psychedelic effects that are mediated through other mechanisms (such as other serotonin receptors, or maybe the dopaminergic system). From what I seem to remember (from that neurology lecture, mind you (where I was high)), LSD has some cardiovascular effects – basically everything you may experience from a large dose of caffein: rapid heartbeat, sweating, nervousness.

Re:Researchers use music and LSD to understand how we attrib... by tachyonbeam on Tuesday January 31, 2017 @01:27AM (#13528244)
LSD has a very wide receptor binding profile, see Table 8 of this paper: http://www.maps.org/research-archive/w3pb/2008/2008_Passie_2...

It also does bind to dopamine receptors, which is why it's more stimulating than other psychedelics.