The Bay Area is about the only place I'd relocate to. I'm picky about what teams I'd want to work for, so the only way I'm going to upend my life, sell my house, buy a house (or find a place to rent) is if I know that I won't have to do it again if things don't work out.

I'd throw LA into the mix too, as it has a growing tech scene and a lot of things going for it. Seattle, Austin, and maybe Boulder if you can survive the cold.