Added: I'm talking about implementing specific, optimized hash functions on 128-bit values (e.g. GUIDs, IPv6 addresses), and not generic hash functions that can take any length input (although many of them speed up linearly in the size of int that gets used internally).
Hashers provide conveniences for feeding in a u8, u16, u32, u64, etc., but most hashers just implement this as casting the value to an array of bytes and using the generic implementation. This is because most algorithms are defined in terms of bytes. Evidently there isn't any interesting optimization to do by statically knowing you have a u32 vs a u64 for these algorithms (appears to be the case for SipHash, XXHash, and Fnv).
And indeed, u128 continues this tradition in the PR: https://github.com/rust-lang/rust/pull/37900/files#diff-2327...