Also in Europe, but I've seen adverts using .travel domains (which are a bit older than most), like egypt.travel and ecuador.travel.
City domains, like sadiq.london.
Admittedly, I can't remember any publicity of the weirder ones, like .lol or .xyz.
It depends on the audience. If you have a non-technical audience or you are e-commerce a .com is basically a necessity still.