Yes there are important differences between running a dev server on VirtualBox and a prod server on one of the above, but there is parity in the workflow. The same is true when thinking about docker-machine + docker, locally then remotely.

I understand that Hyper's cli is quite similar to docker's cli. But my preference is to not consider it seriously until I can bang against a version of the Hyper backend running locally. If that's not forthcoming, fine, Hyper's not for me. :-) If it is, then great! I can't wait to play with it, locally, on my personal computer/s.