I did, some, in the beginning (circa 2006): I was stymied mostly by the realization that deep, deep knowledge of the kernel structures was required to make use of DTrace (I wasn't working as a kernel engineer per se at the time.)

I forgot a lot of it in the meanwhile: just yesterday I was trying to get a simple ustack() using DTrace on a running process, and I even pulled open "Solaris Performance and Tools", and eventually when the process finished, I threw up my hands in frustration. All I wanted to do was see why the running process (oggenc) was taking so long. (But this BPF thing looks far, far more complicated and convoluted than D.)

Nevertheless, I think D is ideal, because, in my case, it plays on my experience in programming AWK: apart from needing to know what in the kernel I wanted to probe, I could immediately start writing DTrace programs without having to learn the language. And that is amazing.