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Re:Twitter clients that can filter tweets by regex? by uuid on Sunday April 18, 2010 @07:37AM (#1274700)
Twitter clients on the desktop suck.

yorufukurou does regex and is generally tolerable (OS X) http://sites.google.com/site/yorufukurou/home-en

Apart from that, it's easy to roll your own stuff - for example using the tweepy python library.

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