> Another thing is if you lug your computer around a lot, I often go from one 3-monitor setup at work to another at home however this always messes up my window placement and I haven't seem to found any DE/WM which handles this cleanly in a convenient way even near the experience on macOS.

Have you tried a tiling WM like i3? If you unplug and replug monitors you're just changing what workspaces are displayed where. The experience is identical if you have one or many monitors.