Re:Show HN: I invented a caffeinated toothpaste
by btym on Thursday September 15, 2016 @07:42PM
(#12510794)
I tried to find some comparable studies, here's one that seems particularly relevant, showing the effects of caffeinated gum:
http://www.militaryenergygum.com/wp-content/uploads/Bioavail... (take a look at the second graph)
TL;DR: Yes, even with oral absorption, you probably won't feel anything after 5 minutes, and you'll be wired at 15 minutes.
This toothpaste definitely won't work "on the spot", but 10-15 minutes is still quick enough to get you going by the time you're dressed and out the door.
Re:Show HN: I invented a caffeinated toothpaste
by girvo on Thursday September 15, 2016 @07:31PM
(#12510733)
Sublingual administration of certain chemicals allows for they bypass of first-pass metabolism; basically going from the thin membranes in your mouth directly into your bloodstream.
I read that caffeine in coffee form takes 15-20 min to be felt by the user. I'm curious how the toothpaste form works on the spot.