At ZenHub, we have already starting working on some integrations with this functionality which you can read more about here - https://www.zenhub.com/blog/dispatches-from-github-universe/

Our focus is going to remain on how to integrate a full-featured project management suite within the GitHub eco-system. The GitHub projects release will make a great foundation, and ZenHub will be there to provide the more advanced features like issue hierarchy (epics), time estimation and reporting. Lots of exciting releases coming soon for ZenHub users :)