> I've met creationists that believed in micro evolution: microbe can evolve to get certain resistance. But not the macro one, that is natural selection can result in human as we are right now. I was absolutely not able to justify the probability that it can happen.

At that point they aren't arguing against evolution so much as they are cosmology, geology, physics etc. The only difference between micro/macro evolution is the timescales involved and the timescale is what they don't accept.