It should be noted that Fleming discovered Pencillin and the statement is especially prescient coming from him. He spoke countless times around the world trying to raise awareness that antibiotic resistance would be inevitable when used improperly.

The nightmare scenario is medical science gets rolled back by a century as non-trivial infections return to being a death sentence.

OK and how do you locate and invoice all of these morally responsible individuals who have led to this resistance? It's hundreds of thousands of doctors. I doubt their malpractice insurance will cover this. And then aside from the unnecessary prescriptions, because the ignorant patient-consumer demanded it, is the ignorant patient-consumer who doesn't take the entire prescribed dosage which is itself the far bigger problem that lead to resistance. How are they punished and insured for their immorality?

I think you've mistaken moral for legal. We don't punish immorality except through social and cultural pressure, or to make it a legal issue, and then we aren't punishing morality so much as legality (even if rooted in morality).