Re:First new antibiotic in 30 years discovered in major brea...
by JoeAltmaier on Monday September 05, 2016 @09:09AM
(#12430033)
Not necessary. According to the paper
Its no more possible that a cell could become resistant, than you or I could become resistant to having our head blown off.
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Re:First new antibiotic in 30 years discovered in major brea...
by gpvos on Monday September 05, 2016 @09:34AM
(#12430174)
Does it also inhibit cell wall synthesis of non-bacteria cells? If yes, it's toxic to us. If no, bacteria cell walls could evolve to be more like non-bacteria cell walls in order to avoid this. Two links from the Wikipedia article on Teixobactin about this: http://www.the-scientist.com/?articles.view/articleNo/41850/... http://www.bbc.com/news/health-30657486 (Actually, Teixobactin only works on gram-positive bacteria, not on gram-negative ones which have an extra membrane.)
Re:First new antibiotic in 30 years discovered in major brea...
by Turing_Machine on Monday September 05, 2016 @04:04PM
(#12431983)
Only bacteria, plants, fungi, etc. have cell walls. Animals don't have them.
All cells do have a cell membrane, but that's a totally different structure.
Re:First new antibiotic in 30 years discovered in major brea...
by gpvos on Tuesday September 06, 2016 @06:28AM
(#12434878)
Thanks for the correction.
Re:First new antibiotic in 30 years discovered in major brea...
by AstralStorm on Monday September 05, 2016 @09:26AM
(#12430135)
The real mechanism of resistance is in how it inhibits cell wall synthesis. Plus there are general mechanisms such as drug efflux and prevention of drug entry into the cell.
See, it must be specific enough to not kill our cells, otherwise it is worthless.