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A comment on The US government poisoned alcohol during Prohibition (2010). Parent comment

Re:The US government poisoned alcohol during Prohibition (2010) by tpm on Sunday September 04, 2016 @01:38PM (#12425626)
We can very well blame those deaths on MDMA, because the causality is clear.

If you take six pills of anything that exists in pill form and you die, then assuming one pill is something of a standard dose, that means that chemical has a low therapeutic index and is therefore dangerous.

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Re:The US government poisoned alcohol during Prohibition (2010) by montecarl on Sunday September 04, 2016 @03:11PM (#12426157)
This is actually not that different from the therapeutic index of paracetamol (Tylenol)[1]. Paracetamol is a super safe drug when used exactly as directed (both dosage and not taking with alcohol), but taking any more than prescribed can be fatal.

[1] https://en.wikipedia.org/wiki/Paracetamol_toxicity

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Re:The US government poisoned alcohol during Prohibition (2010) by tpm on Sunday September 04, 2016 @05:43PM (#12426870)
Exactly. Thankfully nobody is claiming that paracetamol is not killing people - quite clearly, it is. As is MDMA, even if it's quite safe (and fun) to use in most cases.
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Re:The US government poisoned alcohol during Prohibition (2010) by s_q_b on Sunday September 04, 2016 @07:19PM (#12427199)
Well... paracetamol is a modern day denaturing agent. Under DEA influence, paracetamol is included many opiate painkillers to "deter abuse."
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Re:The US government poisoned alcohol during Prohibition (2010) by DanBC on Sunday September 04, 2016 @07:24PM (#12427213)
Do you have a cite for that?

Most combination meds try to get synergistic benefits - the combination allows you to use lower doses of both active ingredients. (This probably doesn't work, but that was the intent when the meds were created.)

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