No, because the WHOIS details on the domain can change without ownership actually having changed, in the not-uncommon case where a domain starts out registered by a founder or early employee and is later transferred to the company proper.

Given the prevalence bogus WHOIS data, the inverse is also possible: if the 2nd owner uses the same registrar and "privacy-protection" feature as the original owner, the WHOIS data could appear to have not changed, except for the start date of the registration, which would look identical to a single owner who re-registered their domain after allowing it to lapse.