Empirical religion ftw.
> "Of course you are uncertain, Kalamas. Of course you are in doubt. When there are reasons for doubt, uncertainty is born. So in this case, Kalamas, don't go by reports, by legends, by traditions, by scripture, by logical conjecture, by inference, by analogies, by agreement through pondering views, by probability, or by the thought, 'This contemplative is our teacher.' When you know for yourselves that, 'These qualities are unskillful; these qualities are blameworthy; these qualities are criticized by the wise; these qualities, when adopted & carried out, lead to harm & to suffering' — then you should abandon them.
http://www.accesstoinsight.org/tipitaka/an/an03/an03.065.tha...
The XYZ fact may turn out to actually not generalize. With mental phenomena, often how you got somewhere matters more than the thing itself. For a nice negative example, think about taste - many of us have strong repulsion towards some foods caused by random events in the past. Like, for many years parsley made me nauseous, and it started when as a kid I ate a broth and then threw up. It's a common thing that when you're sick your brain can create associations between how you feel and what you smell or eat. So you end up hating some food not because it's objectively bad, not because everyone else hates it too, but because of a random event in your life that happened to get associated with it.
I treat n=1 experiments as a way to probe such random associations. If you find out that something works for you, it doesn't matter that it isn't scientifically proven. It doesn't matter the effect doesn't generalize. It doesn't matter it works only through association and that this association was created due to you doing the experiment. If it works for you, it works for you.
But to be clear - "it works for me" is the only thing you can say in such case. N=1 experiments are ok, but trying to generalize from them isn't. Saying "it must work because it worked for me" based on such experiment is of course quackery.
But that was just my experience of it after a short time (one month)--it's an empirical process of consciously observing your own mind (and letting things go), which is fascinating, and leads to continuous changes in how you interact with the world and others in it.
http://cordis.europa.eu/project/rcn/192255_en.html
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866254/
http://sleep.stanford.edu/research/recent_publications.html
http://www.nhlbi.nih.gov/about/org/ncsdr/research/
http://www.pennstatehershey.org/web/psychiatry/research/over...
https://www.unisa.edu.au/Education-Arts-and-Social-Sciences/...
http://onlinelibrary.wiley.com/doi/10.1111/jsr.2016.25.issue...
I'm saying this with first hand experience, I was skeptical (I think lazy is better word), but I started recently, been on four weeks now and it is working for me, never going back.
I wish this was true && that there was well compiled evidence that could convince me that this is the case.