News for hackers. Stuff that matters.
Re:Cellphone-Cancer Link Found in Government Study by mikekij on Friday May 27, 2016 @10:56AM (#11786421)
Medical Physicist here. The position isn't "non-ionizing radiation can't cause cancer". It's "There is no known mechanism by which non-ionizing radiation can cause cancer." Maybe we'll discover a mechanism one day to explain this. But we seem to understand the processes by which cell mutations, and subsequently cancer, and produced.

We should certainly research this area further. But the probability of this study having failed to control for some other variable is higher than the probability of an as of yet unknown process allowing microwaves to produce changes in the chemical bonds holding together DNA.

Re:Cellphone-Cancer Link Found in Government Study by dragonwriter on Friday May 27, 2016 @11:38AM (#11786687)
> But we seem to understand the processes by which cell mutations, and subsequently cancer, and produced.

We certainly seem to understand many of the processes by which cell mutations are produced, but that's not the same as all of them, and, perhaps more importantly, what we do understand about how cancer is produced is that there are lots of factors besides cell mutation involved, and those of them that we do understand in general terms aren't understood in detail, and aren't sufficient to explain the entire process.

> But the probability of this study having failed to control for some other variable is higher than the probability of an as of yet unknown process allowing microwaves to produce changes in the chemical bonds holding together DNA.

That seems more like a statement of subjective plausibility than a supportable statement of quantitative probability, and, moreover, in order to be relevant to the result seems also to falsely assume that it is necessary to "produce changes in the chemical bonds holding together DNA" to alter the incidence of cancer. We already know that even when a potentially-cancer-inducing genetic mutation exists, various other non-genetic factors in the body (including qualities of the extracellular matrix around the cells which have the mutation) play significant roles in whether cancer actually develops. Its quite possible that if there is a cellphone-to-cancer link, that the mechanism doesn't involve changes in the frequency of genetic mutation at all, but affects on the body that affect the whether cancer manifests when a potentially-cancer-inducing mutation has arisen through other means.

Re:Cellphone-Cancer Link Found in Government Study by alevskaya on Friday May 27, 2016 @01:34PM (#11787549)
Cancer is complicated, but it emphatically is a _genetic_ disease, with inherited _genetic_ risk factors. Environmental influences are typically mediated by their ability to cause or promote mutation via cell stress (e.g. by promoting local inflammation) and cell proliferation, which in turn increases mutation load. There are subtler influences that could weaken the natural immunosurveillance of neopeptides by T-cells, but the importance of such surveillance in prevention is debated and perhaps more relevant in later-stage cancers. We may not fully understand such a complicated disease, but with modern sequencing we have a pretty good lens on the phenomenology of emergence of cancer, and that "subjective plausibility" is a working gut-bayesian framework that doesn't put a strong prior on ambient microwaves as a likely causative factor. Also, the field of RF- and microwave- induced cancer has been a long-running cottage industry producing bad science for many years now: i.e. studies with poor statistical power and poor replicability… so there’s a reason skepticism prevails on this point among biologists. It’s not just dogmatism: if anyone can get a replicable animal model we could dive into it to find new mechanisms… but these results always seem to sit at the edge of detection.
Re:Cellphone-Cancer Link Found in Government Study by dragonwriter on Friday May 27, 2016 @02:09PM (#11787783)
> Environmental influences are typically mediated by their ability to cause or promote mutation

That may be typical, in that there are definitely lots of environmental influences that work that way, but its been established for at least on the order of a couple of decades that there are also influences that impact the emergence and development of cancer when potentially cancer-causing mutations exist, and that genetics while important to cancer, aren't the whole story and mechanism. Attributes of the extracellular matrix, which can definitely be affected by physical and chemical effects that are not mutagenic, are one of the established influences.

Re:Cellphone-Cancer Link Found in Government Study by tryitnow on Friday May 27, 2016 @11:19AM (#11786552)
"But the probability of this study having failed to control for some other variable is higher than the probability of an as of yet unknown process allowing microwaves to produce changes in the chemical bonds holding together DNA."

I really like this sentence. I wish more science commentators would talk about probability like this.

Re:Cellphone-Cancer Link Found in Government Study by donovanr on Friday May 27, 2016 @11:21AM (#11786561)
I've always been curious: I understand that h.nu from cell phone radiation isn't big enough to ionize (say) DNA, but since the molecules in our body are in thermal equilibrium, can't h.nu + kT get it done every once in a while?

[edited because using an asterisk to denote multiplication was a bad idea]

Re:Cellphone-Cancer Link Found in Government Study by tiplus on Friday May 27, 2016 @12:29PM (#11787079)
kT is very little energy compared to a chemical bond. Take for example [0], they give an excitation energy for water of about 8 electron Volts which is ~750 kJ/mol, whereas kT at room temp is about 2.5 kJ/mol.

[0] http://scitation.aip.org/content/aip/journal/jcp/128/10/10.1...

Re:Cellphone-Cancer Link Found in Government Study by donovanr on Friday May 27, 2016 @07:45PM (#11789862)
Right, but it's the 'every once in a while" part that I wonder about, i.e. the variance of that distribution. Maybe you could argue that since the Maxwell-Boltzmann distribution is narrower the lower its mean, if kT is small then it's an exponentially tiny effect.
Re:Cellphone-Cancer Link Found in Government Study by tiplus on Saturday May 28, 2016 @12:47AM (#11790610)
So yes, kT is small on average (does fluctuate) and it is also 1 kT per degree of freedom. So yes, in principle a few hundreds of atoms could randomly fluctuate in energy to create this effect. However, this is hyper unlikely. I would be suprisd if it happened once in the life time of the universe. Also consider that you cannot create Maxwell demons[1].

[1] https://en.m.wikipedia.org/wiki/Maxwell%27s_demon

Re:Cellphone-Cancer Link Found in Government Study by psychometry on Friday May 27, 2016 @03:43PM (#11788408)
Biostats grad student here.

"But the probability of this study having failed to control for some other variable is higher than..."

It was a randomized block experiment. You don't need to assume that there were no unmeasured confounders in order to make causal inferences. That assumption is only needed in cross-sectional and cohort studies.

Re:Cellphone-Cancer Link Found in Government Study by mangeletti on Friday May 27, 2016 @11:36AM (#11786673)
Conjecture:

There is no such thing as "non-ionizing" radiation. There is just a continuum that ranges from "barely a chance for this to ionize a molecule" to "this will ionize something in the first nanometer". I mean, what's the point of understanding EMR as a continuum of wavelength, if we're going to create arbitrary distinctions therein and presume to know everything about those distinctions.

Another way to think about this is with an analogy: "non-lethal weapons"... but then see https://mic.com/articles/123410/nonlethal-weapons-are-much-m.... It would seem smarter to start thinking about things as "less" and "more" of something, rather than "non".

If you find some wavelength in the middle that seems to be safe, perhaps it is safe in the near term, but when put in terms of "less ionizing than we can notice" it doesn't sound like something I want to hold next to my brain for the next 15 years.

Also note, it's already known that Bluetooth and WiFi cause the blood brain barrier to become 10-100x more biologically leaky[1], letting more chemicals into your brain.

Edit: apparently, this Bluetooth / WiFi point is moot.

1. http://www.ncbi.nlm.nih.gov/pubmed/8012056

Re:Cellphone-Cancer Link Found in Government Study by evgen on Friday May 27, 2016 @12:03PM (#11786883)
Also note, it's already known that Bluetooth and WiFi cause the blood brain barrier to become 10-100x more biologically leaky[1], letting more chemicals into your brain.

No, it is not.

Your source: http://www.ncbi.nlm.nih.gov/pubmed/8012056

No similar effect found at 1439 Mhz: http://www.ncbi.nlm.nih.gov/pubmed/16142770

Replication of experiment at 915 Mhz sees no effect on blood brain barrier: http://www.ncbi.nlm.nih.gov/pubmed/19580497

Do you have any other evidence? So far you are shooting blanks.

Re:Cellphone-Cancer Link Found in Government Study by myblake on Friday May 27, 2016 @11:45AM (#11786745)
It's been a while since I took chemistry and physics so I could be wrong, but I think you may be incorrect due to quantum effects. Specifically, the quantum in quantum mechanics refers to various phenomena which are quantized, a very common example of which is an electron moving to a different energy level. It's entirely discrete what energy levels an electron may orbit an atomic nucleus at, it's not a continuum, and for an electron to receive enough energy to be free of the nucleus (causing the atom to become an ion) requires some minimum energy level. Energy is directly proportional to wavelength in the case of em radiation, so there in fact is some minimum energy required for something to be "ionizing".

It is possible that other mechanisms cause cancer, but your conjecture is almost certainly false. Someone who does this for a living please let me know if there's clarification needed.

Re:Cellphone-Cancer Link Found in Government Study by tiplus on Friday May 27, 2016 @12:22PM (#11787027)
You are somewhat correct. In principle the system is quantized but due to the sheer number of degrees of freedom (or quantum states) the spectra may still appear continuous.

Take for example a single water molecule in vacuum: If you calculate the QM vibrational (motion of the nuclei) and electronic frequencies you would conclude that there is no way that microwave radiation can excite a water molecule. This is because the nuclei interact with three discrete (quantized) frequencies in the infrared (IR light), whereas the electronic degrees of freedom only interact with much higher energy photons (UV and above).

However, if you now move into the bulk, you will notice that there are is also an interaction energy between the water molecules which causes rapid changes in the water conformation at room temperature. From the quantum mechanical perspective, you now get an explosion of possible states including states which excite the hydrogen bond network between the water molecules. You can now induce translation and rotation of water with respect to each other. This is why water absorbs across a large spectrum of frequencies including radiation in the microwave region.

For DNA, the situation is similar. You will also find a continuous broadening of states. BUT how well you absorb energy at a given frequency still varies. Cell phone bands do not carry enough energy to break electronic bonds directly (unlike UV light). Instead, you can only induce thermal motions of the nuclei (heat). Luckily, our DNA transfers excess heat very rapidly (~picoseconds) to its environment, so no danger of local heating to the point of bond breaking if you don't climb up a massive cell phone tower.

In the end, its very unlikely that cell phone radiation alters chemical bonds in our DNA. However, beware of the sun while talking on the phone! I would guess that outdoor usage of cell phone significantly increases the dangers of cell phone usage. ;-)

Re:Cellphone-Cancer Link Found in Government Study by mangeletti on Friday May 27, 2016 @11:53AM (#11786815)
Re:Cellphone-Cancer Link Found in Government Study by bittercynic on Friday May 27, 2016 @11:44AM (#11786734)
If a photon doesn't have enough energy to knock an electron out of it's orbital, then it won't. This is not a probabilistic thing.

Do you have a source for the blood-brain barrier thing?

Re:Cellphone-Cancer Link Found in Government Study by tedsanders on Friday May 27, 2016 @12:12PM (#11786958)
It is a probabilistic thing. If your photon arrives at the same time as another photon, then you can have two-photon absorption (which wouldn't have occurred without your photon). Ditto if your photon arrives at the same time as a thermal vibration or any other carrier of energy. This is why semiconductors can still occasionally absorb photons with energy below their bandgap. Anything in a thermal environment has some chance of being excited, and adding extra radiation will only increase those chances.

Furthermore, if we want to get really technical and into even lower probabilities, photons don't have single well defined energies. Wavelengths are not singularly defined for waves that don't extend to infinity. Therefore, even radiation that is emitted around, say, 500 nm, still has a small of chance of being absorbed by a 499 nm transition. Obviously these probabilities get tiny as the difference gets large, but they never drop to 0, technically.

I'm not saying any of this is medically relevant, but practically everything that is quantum mechanical is probabilistic.

(I have a PhD in physics, focusing on experimental quantum mechanics)

Re:Cellphone-Cancer Link Found in Government Study by bittercynic on Friday May 27, 2016 @01:09PM (#11787361)
It's exhilarating to have a long-held belief broken. Thank you!

Two-photon absorption becomes an important effect at high intensities (if I understand the wikipedia article). How do "high intensities" compare to the intensity of radiation from a phone?

Re:Cellphone-Cancer Link Found in Government Study by mangeletti on Friday May 27, 2016 @11:46AM (#11786753)
See update (added footnote).
Re:Cellphone-Cancer Link Found in Government Study by snerbles on Friday May 27, 2016 @11:58AM (#11786861)
WiFi and Bluetooth do not operate in the 900 MHz band.
Re:Cellphone-Cancer Link Found in Government Study by EthanHeilman on Friday May 27, 2016 @11:46AM (#11786750)
> Bluetooth and WiFi cause the blood brain barrier to become 10-100x more biologically leaky, letting more chemicals into your brain.

Can you recommend a good source on this? It seems like 10-100x more "leaky" BBB would have some pretty serious consequences.

Re:Cellphone-Cancer Link Found in Government Study by mangeletti on Friday May 27, 2016 @11:47AM (#11786766)
See update (added footnote).
Re:Cellphone-Cancer Link Found in Government Study by CorvusCrypto on Friday May 27, 2016 @01:16PM (#11787429)
My first thought was "damn, those exposure powers are extremely high".

Think about it... even the 0.5 W/kg treatment is still about 40W for average human adolescent male. That's a LOT of power from just a cell phone