I once had to drive myself few hundred kilometers back home after a discharge from a psych ward - i was taking some new variation of activisation pill intended to make me less apathetic. While usually I am super careful, will yield/brake preventively to avoid an accident (haven't had one yet - in big part thanks to mindfulness and survival instict) - in the begining that medicine just threw it out the window. I quite literally YOLO'd head on with an 18-wheeler because my brain just went OVERTAKE NOW, BITCH. (did not crash, it was just incredibly stupid and tight) Took me some time to adjust and stop being riddiculously reckless.

Same with nausea suppression pills for travel. I was once made to drive after taking one.

I'd venture to say that the lower likelyhood of an accident while on cocaine would come from most people that not pay any goddamn attention to anything, frantically scanning everything: the road, traffic, road shoulder, pedestrains, etc, etc