If you're ready to throw a bit of money at it (and you're playing on Windows) I'd recommend having a look at Innerspace from Lavishsoftware.

I used that to bot on WOW back in the day, this tool was fabulous and can be adapted to probably any game. Knowledge of C++ is required to create an extension, after that you can code your bot in C# or Lavishcript (their own script language, quite powerful).