It's very hard to say, because of the use of parallel construction. We know very little about what the NSA does with its data; even members of Congress are being denied access to this information. But we do know for a fact that the DEA has prosecuted people based on information they received from the NSA.

https://en.wikipedia.org/wiki/Parallel_construction http://www.reuters.com/article/us-dea-sod-idUSBRE97409R20130...