...or just use a preset someone else made:
Now that's thinking the npm way
Especially since this preset is two lines long, referring to two other plugins
Re:Node.js v6.0 Released
by jsprogrammer on Tuesday April 26, 2016 @03:41PM
(#11574934)
It looks like the primary thing missing is 'iterator closing'.
So take the Node 6.0 compatibility table, find out what features it supports and create a "Babel preset" that has those excluded.