Re:Elimination of HIV-1 Genomes by CRISPR/Cas9 Gene Editing
by fndjdh on Tuesday March 29, 2016 @01:12PM
(#11382988)
>If you're going to deliver enough lentivirus into an HIV patient to edit all the HIV out of their T-cells, you're going to provoke a massive immune response.
Not if the HIV infection has progressed to AIDS. Even with a regular HIV infection the immune response would be diminished.
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Re:Elimination of HIV-1 Genomes by CRISPR/Cas9 Gene Editing
by astazangasta on Tuesday March 29, 2016 @01:35PM
(#11383192)
No; HIV targets CD4+ T cells; you will still have CD8s being activated by the lentivirus all over the body and killing cells in response.