AFAIK, dramamine is still pretty popular for sea sickness. It's what I use if I need it. Like other antihistamines, though, it makes me really groggy so that may be the effect as much anything. Other things I hear people using are Scolpamine patches and just wristbands; no personal experience in either case.

I find being on deck and actively engaged helps me a lot too. For this reason, I suspect that I wouldn't be particularly bothered by VR but I've never had an opportunity to check it out thoroughly. You get to just sitting and going to yourself "I will not get seasick" tends to lead to problems.