Check out Tab Outliner[1] for Chrome. Its integration into the Chrome UI is not as good as Tree Style Tab's in Firefox but is has better keyboard shortcuts, rearranging tabs with Drag and Drop is more intuitive and its built in session manager allows you to unload entrie trees from RAM without losing the tab hierarchy.

This enables a workflow with several hundreds of tabs without the drawback of the additional RAM and CPU usage. Previously I shared the impression that Tree Style Tab for Firefox has ruined all other browsers for me and I could never switch away from Firefox but Tab Outliner showed me that I was wrong.

[1]http://tabsoutliner.com/