Yes. Back when I still used Windows five years ago, the app was an essential tool for me. All web browsers, downloaders and basically anything else that I consider high risk must be run in a sandbox, which is routinely emptied. Less risky apps are sometimes also installed in a sandbox, which is emptied much less frequently. And it's great for trying out trial versions of software before I fully trust their publishers. I didn't run any antivirus on that machine at all and I'm that confident. Nowadays I've switched to OS X but I still miss the easy sandboxing of basically any app.