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Re:Show HN: PyGeno, a Python Package for Precision Medicine by theophrastus on Tuesday February 23, 2016 @01:06PM (#11160893)
Apologies for a trivial objection: but the serpentine icon associated with this, likely otherwise fine, package embodies an odd little annoyance to all us structural biochemists: It depicts the DNA helix as left-handed. This is a rare form of DNA at best, most likely an unlucky graphical choice, and causes many nerdy folk to suspect that you don't know what you're doing. If you think i'm nuts (and hey maybe...) there are entire websites devoted to this error, because for some reason it's a common error and makes our eyes bleed [wink]: http://users.fred.net/tds/leftdna/
Re:Show HN: PyGeno, a Python Package for Precision Medicine by mrestko on Tuesday February 23, 2016 @02:13PM (#11161471)
Other nerdy folks will be happy to grant that an icon is merely that and not intended to be a perfect embodiment of a molecule.
Re:Show HN: PyGeno, a Python Package for Precision Medicine by lvs on Tuesday February 23, 2016 @02:50PM (#11161746)
Those folks lack expertise in the domain. Sequences are simply abstract representations of real molecules, and knowledge of sequence means very little without exercising effort and rigor to understand structure and function.