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Re:Show HN: PyGeno, a Python Package for Precision Medicine by Abundnce10 on Tuesday February 23, 2016 @12:50PM (#11160757)
It's times like these that I wish I had a better understanding of biology/chemistry/genetics. I fancy myself a Python/data person, does anyone have any advice on what to read to begin understanding how to utilize a package like this?
Re:Show HN: PyGeno, a Python Package for Precision Medicine by cing on Tuesday February 23, 2016 @12:55PM (#11160800)
Re:Show HN: PyGeno, a Python Package for Precision Medicine by czyzc on Tuesday February 23, 2016 @01:57PM (#11161319)
Lior Pachter on read alignment in general is a good start[1]. This package seems to modify the human reference genome based on the known mutations a person has, making it easier to map an exon back to a genomic position.

[1] https://liorpachter.wordpress.com/2015/11/01/what-is-a-read-...