We happily incarcerate and (for countries that do so) execute people based on much weaker evidence. 2^-80 is absurdly small, to the point that essentially any other possibility is more likely.

You say you want to see it twice, but one data point with an error rate of 1 in 2^80 is, statistically, about a billion times more convincing than a million observations with an error rate of 1 in a million.

(That being said, there are a lot of of explanations that don't involve malice, including honest error, bugs in any of the software products involved in the process, etc. But no, I don't believe that this was a 1 in 2^80 fluke.)