How many software developer jobs do you need? 1222 sounds like it would provide quite a bit of choice. Plus, there's probably fewer people looking for those jobs in Portland. Not to mention the fact that the salary is 20% higher in SF, but rent is 60% higher in SF [1]. I'd say that's a pretty big win for Portland.

[1] http://www.numbeo.com/cost-of-living/compare_cities.jsp?coun...