As I've gotten older I don't tolerate contacts as well so most of my usage (dev unit v2 in my case) has been with glasses. My prescription is fairly strong so I already get a bit of distortion in peripheral vision. It's something I tune out in reality but in VR, it took a few minutes of getting used to. It wasn't bad but it's a lot like when you first put on a headset and you sort of learn to gaze straight ahead rather than looking at stuff at the edges of your vision while still looking forward.