I dunno. I think people with edge case emails (i.e. those not easily validated with a simpleish regex) should be nudged towards getting more standardized emails.

Our company won't accept weird emails for free trial sign ups. We should be nudging users towards good behavior.

Of course, if your email address is provided at the corp level, then you don't have as many options.

Non-standard emails can be used as tools for phishing is another reason why we should not validate them.