They definitely exist, I used to work in this building:

http://www.americantwine.com

Here's another example:

http://www.thecmaninn.com/claremont/about-us/history.aspx

Here's an older paper from the state of RI:

http://www.planning.ri.gov/documents/tp/TP%20150.pdf

So one note from that paper: northern RI alone had 10mil sq ft of vacant mill building space.

That's a lot. It will take a lot of rebuilding to come close to reclaiming all the space in those old buildings.

Also, those old buildings didn't always take into account things like, say, HVAC efficiency. That kind of retrofitting takes money.