Re:How the Food Industry Engineers the Need to Eat
by pc86 on Friday December 11, 2015 @11:20AM
(#10717942)
Tumor Necrosis Factor α: A Key Component of the Obesity-Diabetes Link[0]
The hormone resistin links obesity to diabetes[1]
Excerpt:
Type 2 diabetes...is strongly associated with obesity; however, the mechanism by which increased adiposity causes insulin resistance is unclear. Here we show that adipocytes secrete a unique signalling molecule...increased in diet-induced and genetic forms of obesity.
Pigment Epithelium-Derived Factor Contributes to Insulin Resistance in Obesity[2]
Excerpt:
Herein, we show that the noninhibitory serine protease inhibitor, pigment epithelium-derived factor (PEDF), plays a causal role in insulin resistance. Adipocyte PEDF expression and serum levels are elevated in several rodent models of obesity and reduced upon weight loss and insulin sensitization.
The hormone resistin links obesity to diabetes[1]
Excerpt:
Type 2 diabetes...is strongly associated with obesity; however, the mechanism by which increased adiposity causes insulin resistance is unclear. Here we show that adipocytes secrete a unique signalling molecule...increased in diet-induced and genetic forms of obesity.
Pigment Epithelium-Derived Factor Contributes to Insulin Resistance in Obesity[2]
Excerpt:
Herein, we show that the noninhibitory serine protease inhibitor, pigment epithelium-derived factor (PEDF), plays a causal role in insulin resistance. Adipocyte PEDF expression and serum levels are elevated in several rodent models of obesity and reduced upon weight loss and insulin sensitization.
[0] http://diabetes.diabetesjournals.org/content/43/11/1271.shor...
[1] http://www.nature.com/nature/journal/v409/n6818/full/409307a...
[2] http://www.sciencedirect.com/science/article/pii/S1550413109...