But typescript will get you most of the "quick wins" of type safety and is very easy to migrate to, so it's probably a better choice in the short and medium term (at least in terms of immediate productivity).
I'm more into a long haul so scala sounds pretty cool.
But what just rushed into my mind is that angular 2 will be in typescript so learning scala would only be relevant for server side code. And using two languages when one can handle both doesnt sound quite convicing :/ Would you still recommend scala when I want to work with angular 2 in the near future?
All that said, if you're thoroughly committed to Angular 2 (a mentality I don't really understand - I love Wicket but if an equally OO framework existed in native Scala then I'd use that instead) then using anything other than Typescript is probably an unnecessary risk factor.
Babel and ES6 should be fine too.
Do you think switching to react would be worth it? My angular pages are not very complex and I'm still relatively new to angular so switching could be possible.
For example, look at this: https://docs.angularjs.org/api/ng/directive/ngOptions
Why would you want to learn this kind of obscure syntax, just to make a simple select input (and still be limited in what you can do)? You don't need this kind of stuff in React because you build your views with pure Javascript and HTML.
It's not about Facebook - it's about the design that promotes "functionality" and modularity etc. That's the big deal.
Angular and Ember are both needlessly complicated to begin with, but even more so because of all the two-way state-mangling going on.
So yes, switching to React will be ever-increasingly worth it, because the benefits of not having to deal with Angular will keep compounding over time.
So instead of "opportunity costs", you'll have "opportunity benefits" :P