The Ergodox design has one very significant advance over standard keyboards (besides the NKRO), the large cluster of buttons accessible to each thumb. The glaring omission is the the lack of any kind of mouse-pointer control. It's an odd decision to spend maybe $240 US https://www.indiegogo.com/projects/ergodox-ez-an-incredible-... on a keyboard that will still leave you moving your hand on and off your mouse all day. Come to think of it, for that kind of money it would be nice to get Velotype http://www.velotype.com/en/ / Veyboard http://www.veyboard.nl/ -style wrist keys as well.