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A comment on Vitamin C kills tumor cells with hard-to-treat mutation in mice. Parent comment

Re:Vitamin C kills tumor cells with hard-to-treat mutation i... by Amorymeltzer on Monday November 09, 2015 @03:18PM (#10535516)
No of course not. It does mean that this particular pathway is very different in the mouse model, and studies of vitamin C and mice should be taken with an extra grain of salt.
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Re:Vitamin C kills tumor cells with hard-to-treat mutation i... by cjhveal on Monday November 09, 2015 @03:28PM (#10535577)
In this regard, I think we agree very much! I simply wanted to point out that the specific example that they endogenously synthesize ascorbic acid wasn't a great reason for why this particular trial wouldn't be valid.

Be skeptical of any scientific claim made, especially around possible links between animal models and human clinical environment, and even more especially when the systems involved are not highly conserved cross species.

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