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Re:Thinking positively: The genetics of high intelligence by Mz on Monday November 02, 2015 @06:34PM (#10496192)
Of course it is possible that there are alleles with a large positive effects on intelligence, but is very unlikely because of the complexity of human intelligence.

Some years ago, I read something that suggested otherwise. IIRC, it suggested that we had some idea of what alleles positively influenced intelligence based on the fact that Ashkenazi Jews were something like 2% of the population but had won something like 10% of Nobel Prizes and about 60% of the population had one or more alleles for serious genetic disorders known to impact neurology.

I remember this in part because, although I am not Jewish, I have one of the genetic disorders they tend to carry.

Re:Thinking positively: The genetics of high intelligence by danieltillett on Monday November 02, 2015 @06:47PM (#10496290)
It is in principle possible for a sub-popualtion like Ashkenazi Jews to have a higher mean intelligence and hence many more individual with extremely high intelligence without there being alleles with large affects on intelligence. It would just mean that they have a higher frequency of the small positive effect alleles. More importantly, people have looked for such alleles in the Ashkenazi population and have failed to find them.

As far as I am aware there in no genetic disorder that only Ashkenazi’s suffer from that is not also present in the rest of the human population, the only difference is frequency.

Re:Thinking positively: The genetics of high intelligence by cba9 on Tuesday November 03, 2015 @08:38PM (#10504020)
> More importantly, people have looked for such alleles in the Ashkenazi population and have failed to find them.

They have? I'm not aware of any GWASes targeting intelligence using Ashkenazi samples.

Re:Thinking positively: The genetics of high intelligence by Mz on Monday November 02, 2015 @06:52PM (#10496314)
It is in principle possible for a sub-popualtion like Ashkenazi Jews to have a higher mean intelligence ...

As far as I am aware there in no genetic disorder that only Ashkenazi’s suffer from that is not also present in the rest of the human population, the only difference is frequency.

Do you honestly see no possible connection between these two things?

That's a serious question, not intended as argumentative per se.

Re:Thinking positively: The genetics of high intelligence by danieltillett on Monday November 02, 2015 @07:07PM (#10496406)
I think what you are asking is do I think there is any connection between the sorts of mutations found more frequently in the Ashkenazi population and intelligence and the answer is there may well be some, but the contribution for any one mutation is very small.

I don’t think anyone has shown that being a carrier for any of the common mutations found in the Ashkenazi population increases intelligence in a measurable way, but if anyone knows of such a study I would love to read it.

Re:Thinking positively: The genetics of high intelligence by Mz on Monday November 02, 2015 @07:13PM (#10496433)
One of my best search skills appears to be ego surfing, so here is a link from a previous discussion I participated in about ten years ago:

www.kuro5hin.org/story/2005/7/29/20293/9910

Edit: It contains the stats I was trying to reference above but was misremembering. They are 3% of the population and 27% of U.S. Nobel Prize winners.

Re:Thinking positively: The genetics of high intelligence by danieltillett on Monday November 02, 2015 @07:44PM (#10496566)
Yes Ashkenazi Jews are found disproportionally in professions where having a high intelligence increases the probability of success, however, no one really knows why. It is possible that it is genetic (I would be surprised if there was not at least some genetic component), but it could also be cultural.