I accidentally ran over my Yubikey with my Honda Accord, on a key ring with a fin key (1). I dusted it off and it works fine 6 months later. Seriously, if you're in a position where you're using a Yubikey, getting another Yubikey isn't that big a deal for the organization. In fact, if you're a solo practitioner using something like Yubikey, I recommend you get another one and just keep it in a lock box in the event you, say, run over the primary with your car :)

(1) http://www.amazon.com/FCS-Moulded-Steel-Fin-Key/dp/B003JCQPX...