Mortality in People with ADHD [pdf]

Re:Mortality in People with ADHD [pdf] by unfasten on Thursday September 24, 2015 @06:18AM (#10270786)

    All-cause mortality was 5.85 per 10,000 person–years among people 
    with ADHD, compared with 2.21 per 10,000 person–years in people without ADHD. The risk of death 
    among people with ADHD was more than double that in the general population (adjusted mortality rate 
    ratio [MRR]=2.07, 95% confidence interval [CI] 1.70 to 2.50, p<0.0001).

They then give the mortality rates for those diagnosed with ADHD another disorder or substance misuse issues:

    Age at diagnosis of ADHD was associated with mortality, with the risk of death highest among people 
    diagnosed in adulthood (adjusted MRR=4.25, 95% CI 3.03 to 5.78). Mortality among people with ADHD 
    was also affected by comorbid oppositional defiant disorder or conduct disorder (adjusted MRR=2.17, 
    95% CI 1.33 to 3.31) and by coexisting substance misuse (adjusted MMR=5.63, 95% CI 3.69 to 8.16). 
    Among people without these comorbid conditions, mortality was higher in girls and women with ADHD 
    (adjusted MRR=2.85, 95% CI 1.56 to 4.71) than in boys and men (MRR=1.27, 95% CI 0.89 to 1.76).

The part I found interesting here, that they don't seem to mention elsewhere in this article, is that the mortality rate for males with ADHD but without the other disorders is actually lower than their general population numbers (2.07 general population vs 1.27 for males without one of those issues). They actually seem to completely ignore it:

    “Even if these complications did not develop, ADHD was still a risk factor for mortality. This could well be 
    because the core problem of impulsiveness is a cause of accidents, and accidents were the major cause 
    of death.

I'm going by the adjusted mortality rate ratio number. If I'm reading this wrong, please let me know.

[ Parent | on HN ]

Re:Mortality in People with ADHD [pdf] by Menge on Thursday September 24, 2015 @06:58AM (#10270910)

> (2.07 general population vs 1.27 for males without one of those issues)

Since substance misuse and the other disorders influence mortality rates of the ADHD population, it is not surprising that they affect mortality in the general population.

For the inference you seem to be making, I think you would need the mortality rate of males with no ADHD AND no substance misuse/etc. Based on the data given, I see no reason to think that is above 1.27.

[ Parent | on HN ]

Re:Mortality in People with ADHD [pdf] by pasbesoin on Thursday September 24, 2015 @11:44AM (#10272241)

I'm just going to requote those excerpts with flowing text:

All-cause mortality was 5.85 per 10,000 person–years among people with ADHD, compared with 2.21 per 10,000 person–years in people without ADHD. The risk of death among people with ADHD was more than double that in the general population (adjusted mortality rate ratio [MRR]=2.07, 95% confidence interval [CI] 1.70 to 2.50, p<0.0001).

Age at diagnosis of ADHD was associated with mortality, with the risk of death highest among people diagnosed in adulthood (adjusted MRR=4.25, 95% CI 3.03 to 5.78). Mortality among people with ADHD was also affected by comorbid oppositional defiant disorder or conduct disorder (adjusted MRR=2.17, 95% CI 1.33 to 3.31) and by coexisting substance misuse (adjusted MMR=5.63, 95% CI 3.69 to 8.16). Among people without these comorbid conditions, mortality was higher in girls and women with ADHD (adjusted MRR=2.85, 95% CI 1.56 to 4.71) than in boys and men (MRR=1.27, 95% CI 0.89 to 1.76).

“Even if these complications did not develop, ADHD was still a risk factor for mortality. This could well be because the core problem of impulsiveness is a cause of accidents, and accidents were the major cause of death.

[ Parent | on HN ]